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Electrochemical Micro-Sensors

Published on 14 January 2020

Direct Analysis of soil, water and biological fluids

  What is Electrochemical micro-sensors

Electrochemical micro-sensor devices offer real-time information on complex environments by coupling a chemically selective layer to an electrochemical transducer. Electrochemical sensors provide a direct conversion of a biological event to an electronic signal. There are four main types of electrochemical sensors: potentiometric or ion-selective electrodes (ISEs), amperometric, impedimetric and transistors (OECT— organic electrochemical transistor, ISFET, etc.)


  • CEA-Leti’s technology can be adapted to curve various optical components—2D & 3D imagers, IR sensors, Microdisplays—for:

    • Human and veterinarian healthcare for monitoring purposes:
    • Wearable devices for noninvasive physiologica monitoring
    • Point-of-care testing and diagnostics
    • Wearable artificial organs
    • Post-surgery infection

  • Environment and industrial studies for monitoring

    • Water and soil quality
    • Inline or in bioreactor process

  What's new?

Electrochemical microfluidic-biosensors offers a wide range of improvements
for both health practitioners and scientists:

  • Compact and low-cost devices
  • Real-time and continuous multi-parametric measurement
  • Biocompatible, flexible or pitch medium
  • Autonomous devices: wireless communication, low energy consumption
  • Formulation of sensitive and bio-sensitive layers for specific electrochemical detection
  • Form factor, level of robustness depending on the application

The range of parameters measured covers: pH, Sodium (Na+), Potassium (K+), Calcium (Ca2+), Ammonium (NH4+), Carbon dioxide (CO2), Nitrate/nitrite (NO3-/ NO2-), Nitrogen monoxide (NO), Glucose (H2O2), Lactic acide, Creatinine.

  What's next?

CEA-Leti’s team is currently developing:

  • Electrochemical sensors integrated into a microfluidic device—lab on a chip
  • Sensor networks for both cell culture and organ-on-chip
  • Resorbable sensors
  • Sensors on paper
  • Liquid gated field effect transistors (LGFET) based on graphene
  • Coupling OECT and LGFET for design Boolean electrochemical sensors

Additional parameters are coming soon: Magnesium (Mg2+), Fluorine (F-), Phosphate (PO4-), Urea, heavy metal (Lead, Cadmium, Mercury, etc.), Arsenic


 3 patents

  •       FLYER

    (180 ko)